Readers Forum Indian Pediatrics 2005; 42:1007 |
Reply |
Without going into the pros and cons of 6,10,14 weeks and 8,16,24 weeks, it is worth while following the latest WHO schedule for DTwP and HB Vaccine which is highly immunogenic and has established high field efficacy since 1975 and 2000 respectively. No doubt, increasing interval between the 3 doses of the same vaccine, enhances the immunogenicity, GMT, etc. However, the minimum protective antibody level achieved through wider coverage at short interval with excellent field efficacy, have resulted in successful elimination/eradication of the targeted diseases in countries world over using the WHO schedule. A. Parthasarathy, |