A 6-year-old girl was brought to our hospital with swelling of lower
lip, along with blackish discoloration; the upper lip and the gingiva
were also involved. The lower lip was swollen along with areas of
erosion, crusting and necrosis (Fig. 1). The parents
revealed that the lesion started as small vesicles in her lips and
gingiva couple of days ago. The girl complained of burning sensation,
tingling and difficulty in swallowing along with foul breath. On
examination, there were few tiny vesicles grouped on an erythematous
base; the major part of lips was swollen and covered with blackish
necrotic crusts and erosions (Fig. 1). The tongue, tonsils
and posterior pharynx were not involved. The rest of the skin, mucosa
and systemic examination were non-contributory, except for cervical
lymphadenopathy. Tzanck smear examination from an intact vesicle showed
multinucleate, epidermal giant cells.
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Fig. 1 Herpetic gingivostomatitis.
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A diagnosis of herpetic gingivostomatitis was made,
and she was prescribed oral acyclovir, paracetamol and topical
anaesthetic gel. The symptoms subsided and her lips and gum were almost
normal after 7 days (Fig. 2).
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Fig. 2 Post-treatment photograph
showing almost complete resolution.
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Herpetic gingivostomatitis, caused by HSV-1, develops
particularly in children and young adults. The major differentials are
drug induced mucositis (history of exposure to offending drug),
Stevens-Johnson syndrome (exposure to offending drug, target lesions),
streptococcal infection, aphthous stomatitis (canker sores) and
Diphtheria (involvement of tonsillar pillars; pseudo membrane). Tzanck
smear findings and the remarkable response to acyclovir confirmed the
diagnosis of Herpetic gingivostomatitis in our case.