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Indian Pediatr 2014;51: 761 |
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News in Brief |
Gouri Rao Passi,
Email:
[email protected]
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The Ebola Virus Epidemic
In February 2014, in the forested areas of Guinea in
West Africa, the first cases of an unexplained viral hemorrhagic fever
were reported. By March 2014, the Ministry of Health Guinea acknowledged
that this viral hemorrhagic fever had a high mortality rate. Ebola virus
was suspected to be the cause, and subsequently proven when samples were
sent to Senegal and France. Since then cases have been reported also
from adjacent Sierra Leone and Liberia. Nigeria became the fourth West
African country involved in the outbreak when Samuel Patrick, a
US-Liberian citizen infected with Ebola flew into Lagos on 20th July.
Since then, eight people who came in contact with him were infected,
including the doctor and nurse who treated him; the nurse subsequently
died. In Sierra Leone, a high profile doctor who was leading the fight
against Ebola has also died of the disease. Two US aid workers – a
physician and a nurse – were also infected, and were flown out to the US
and given an experimental medication ZMapp. They are being treated by an
infectious disease specialist of Indian origin in Emory Medical
Hospital, Atlanta. Both have shown remarkable improvement. Because of
the high mortality rate and lack of any specific therapy, there is mass
hysteria and bodies of infected people are being left on the streets. A
total of 1779 suspected cases with 961 deaths have been reported by WHO
as on 6th August 2014, of which 1134 cases and 622 deaths have been
laboratory confirmed to be Ebola. This has been the largest epidemic of
Ebola virus with maximum number of deaths since it was first reported
from Democratic Republic of Nigeria in 1976. On 8th August 2014,
the World Health Organization (WHO) declared the outbreak a Public
health emergency of international concern.
Ebola Virus is a viral hemorrhagic fever of the
family Filoviridae. The natural reservoirs are suspected to be animals
(probably bat, pig or monkey) and the first patient is usually infected
from an animal. Human to human transmission occurs via infected
secretions, including urine, stool and blood. Incubation period is 2-21
days. Symptoms are initially non-specific with fever, bodyaches,
vomiting and diarrhea, followed by bleeding due to coagulopathy and
thrombocytopenia. Mortality can go upto 90%. Diagnosis is based on
antibody-capture enzyme-linked immunosorbant assay (ELISA), antigen
detection tests, serum neutralization test, reverse transcriptase
polymerase chain reaction (RT-PCR) assay, electron microscopy and virus
isolation by cell culture. Therapy is supportive with correction of
hydration and coagulopathy. Close physical contact with Ebola patients
should be avoided. Gloves and appropriate personal protective equipment
should be worn when taking care of ill patients at home. Regular hand
washing is required after visiting patients in hospital, as well as
after taking care of patients at home.
There are 47000 Indians in the affected countries and
India placed all of its airports on high alert and stepped up
surveillance of all travellers entering the country from Ebola-affected
regions. (http://www.cdc.gov/vhf/ebola/resources/pdfs/ebola-factsheet.pdf;
www.who.int/mediacentre/factsheets/fs103/en/)
Pediatricians and Poultry Farmers
Why do pediatricians need to worry about poultry
farmers? The answer lies in a very revealing study by the Centre for
Science and Environment (CSE). They took 70 samples of chicken from
various outlets in Delhi, Noida, Gurgaon, Faridabad and Ghaziabad and
tested muscle, liver and kidney tissue for tetracyclines,
fluoroquino-lones and neomycin. They found that 23% contained residues
of one antibiotic, 17% had more than one, and one sample from Gurgaon
actually had a cocktail of 3 antibiotics. Five of the 6 antibiotics
tested for were found in the range of 3.37-131.75
mg/kg. It appears
that poultry farmers indiscriminately use antibiotics both to treat and
prevent infections. It is often mixed with feed to promote growth. This
rampant misuse has led to antibiotic resistant bacteria in chicken.
Subsequently these antibiotics find their way into human beings probably
leading to the development of antibiotic resistant bacteria in humans.
Man does not live in isolation, and in this complex interconnected web,
mistakes by one are paid for by many others. This study is a clarion
call for stricter regulation of antibiotic use in the poultry industry
and controls on the unregulated sale of antibiotics in the industry
(The Hindu 31 July 2014).
Against Violence in Gaza
On 23rd July 2014, The Lancet published an open letter by 24 doctors
and scientists from around Europe against the Israeli violence on
innocent people of Gaza. The letter has a graphic description of the
destruction wreaked by Israeli forces on the people of Gaza, including
the wounded, sick, women and children. Hospitals, clinics, ambulances,
mosques, schools, and press buildings have all been attacked, with
thousands of private homes bombed. They describe it as a ruthless
assault of unlimited duration, extent, and intensity with an aim to
terrorize and wound the soul and the body of the people, and make their
life impossible in the future. The massacres and threats to the medical
personnel in emergency services and denial of entry for international
humanitarian convoys are despicable. They declare that as scientists and
doctors they find it impossible to be silent while this crime against
humanity continues. As they aptly put it these actions "terrifies those
who are not directly hit, and wounds the soul, mind, and resilience of
the young generation." (The Lancet. 2014;384:397-8).
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