A male infant aged 3 months was brought with a maculopapular,
erythematous rash with scaling at the edges distributed symmetrically
over the malar region, forehead, chin and forearms (Fig. 1).
Heart rate was 60/min. Rest of the clinical examination was normal. He
was born to a mother with Systemic Lupus Erythematosus (SLE). ECG was
suggestive of complete heart block. Complete blood counts and metabolic
profile were normal. ANA and DsDNA were negative. A diagnosis of
Neonatal Lupus Erythematosus (NLE) was made.
|
Fig. 1. Erythematous
maculopapular rash with peripheral scaling involving face and
forearms. |
NLE is a rare syndrome affecting infants of less than
six months and having features of rash, cytopenias and complete heart
block in infants born to mothers having Systemic Lupus Erythematosus and
AntiRo and AntiLa antibodies. The rash appears a few days to weeks after
birth and disappears spon-taneously after a few weeks leaving no scar.
Pancytopenias are seldom serious and regress spontaneously. Congenital
heart block may require permanent pacing eventually.
R.G. Holla,
Prabhat Kumar,
Army Hospital (Research & Referral),
Delhi Cantt, Delhi, India.