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Indian Pediatr 2020;57:
749-750 |
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Online Survey of Vitamin D Supplementation Practices in
Children and Adolescents
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Aashima Dabas1, Madhavi Bharadwaj1,
Dheeraj Shah2 and Piyush Gupta2*
Departments of Pediatrics, 1Maulana Azad
Medical College and 2University College of Medical Sciences,
New Delhi, India.
Email:
[email protected]
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We collected information regarding
vitamin D supplementation practices of 230 pediatricians through an
online survey. Routine supplementation was being practiced during
infancy, 1-5 y, 6-10 y, and >10-19 y age by 187 (81.3%), 60 (26.1%), 34
(14.8%) and 41 (17.8%) respondents, respectively. 182 (79%) participants
promoted sunlight exposure, and 171 (74.3%) did not measure serum
25-hydroxy vitamin D levels before supplementation. The survey
highlights that majority of pediatricians prescribe routine vitamin D
supplementation during infancy, but not beyond.
Keywords: Deficiency, Management, Sunlight.
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V itamin D deficiency is considered as a
significant public health problem in Indian children, which can be
prevented by supplementation, fortification and dietary recommendations
[1,2]. The Global Consensus for Nutritional Rickets recommends 400 IU
vitamin D supplementation daily during infancy [3]. Supplementation in
older children is recommended only if symptomatic vitamin D deficiency
or high-risk conditions are present. The Indian Academy of Pediatrics
(IAP) recommends daily supplementation of vitamin D in healthy Indian
children of all ages (newborns till adolescents) to meet the recommended
daily allowance of vitamin D [4]. There are no recommendations yet by
the Government of India for routine vitamin D supplementation. In view
of varying recommendations, we conducted this survey among pediatricians
in India to assess vitamin D supplementation practices for infants and
children.
The data were collected as an online survey through a
Google form by phone (Whatsapp) or e-mail. Participants were selected
from personal contacts with no geographical restrictions. Participant’s
consent was incorporated within the online form. The information was
collected in an anonymous format. Practice parameters were collected
separately for age groups less than 1 year, 1-5 year, 6-10 year and
10-19 year. Approval of the institutional ethics committee was obtained
prior to the conduct of the study.
The survey consisted of 11 close-ended questions to
cover professional experience in years, knowledge about any vitamin D
supplementation guidelines, practice of vitamin D supplementation across
different ages, duration (infrequent if less than 6-12 months/year) and
dose of vitamin D supplementation if practiced, practice of measuring
serum 25-hydroxy vitamin D (25OH-D) before supplementation, and practice
of promoting sunlight exposure. Assuming a prevalence of vitamin D
supplementation as 15% among healthy adolescents, a sample size of 196
respondents was needed with an absolute precision of 5% and 95% level of
confidence.
A total of 230 (140 from private sector) responses
were collected over two weeks. The majority (56%) of respondents had
more than ten-year experience and only 10% were pursuing pediatric
residency. Most (204, 79%) respondents were aware of the national or
international guidelines for vitamin D supplementation. Table
I shows the vitamin D supplementation practices of these respondents
across different age-groups. Eight (3.5%) reported use of a monthly
60,000 IU dose across different age groups. Overall, 182 (79%) promoted
sunlight exposure and 171 (74.3%) did not measure serum 25OH-D levels
before supplementation.
Table I Practice of Pediatricians Regarding Vitamin D Supplementation for Different Age-groups (N=230)
Practice |
Infants |
1-5 y |
6-10 y |
>10-19 y |
Routine supplementation |
187 (81.3) |
60 (26.1) |
34 (14.8) |
41 (17.8) |
Infrequent dosing (<6-12 mo/y) |
26 (13.9) |
16 (26.7%) |
26 (76.5) |
30 (73.2) |
Dose appropriate*
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161 (86.1) |
44 (73.3) |
21 (61.8) |
28 (68.3) |
Data presented as n(%), where n=responses/those practicing
routine supplementation; *Dose 400 IU in infants and 600 IU
beyond infancy [4]. |
The present study highlights that the practice of
routine vitamin D supplementation prescription was mostly limited to
infancy, with a minority practicing routine vitamin D supplementation
beyond infancy in the recommended doses [4]. The recent Comprehensive
National Nutrition Survey [5] reported low prevalence (14-24%) of
vitamin D deficiency (serum 25OH-D <12ng/mL) in Indian children beyond
infancy, raising concerns over need of routine vitamin D supplementation
in apparently healthy children in this age. A cohort study on annual
vitamin D prescriptions of over two million children from UK showed
26-fold rise in prescribing trend between 2008-2016 with maximum rise in
adolescent age group (higher for girls than boys) [6]. There were 24
different dosing regimens used with pharmacological doses (>1000 IU/day)
prescribed in 42.8% children with insufficient vitamin D levels,
suggestive of poor compliance to national guidelines [6].
The meager supplementation rates in older children in
the present study probably were related to absence of felt-need for
vitamin D supplementation in this age-group. The limitation of this
study was that the information was self-reported, and no physical
verification of prescriptions was done. Moreover, the data were
collected from only opt-in respondents who could be contacted personally
by the study team, which may have introduced selection bias. Information
on geographical location of participants and the seasonal preferences
was not collected.
To conclude, the present survey highlights the varied
vitamin D supplementation practices among pediatricians with majority
prescribing supplementation during infancy but not for older children
and adolescents.
Ethical clearance: Institutional ethics committee
of Maulana Azad Medical College, New Delhi; 73/01/2020/41, dated March
13, 2020.
Contributors: PG, DS: conceived the study and its
design; AD, MB: data collection, analysis and drafting the manuscript;
PG, DS: critical inputs to drafting of manuscript. All authors approved
the final manuscript.
Funding: None; Competing interest: None
stated.
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