A 5-year-old girl presented with a rapidly growing,
nontender swelling in her pretibial region. There was
history of repetitive hits of the tricycle pedals on the
shins. A solid subcutaneous mass was palpated. Laboratory
tests were unremarkable. Magnetic-resonance-imaging showed a
hyperintense sub-cutaneous mass and a hyperintense area
consistent with bone marrow edema. As malignancy was a
concern, excisional biopsy was performed. Histopathological
examination revealed subcutaneous granuloma annulare (SGA).
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Fig. 1 Subcutaneous mass in
the left pretibial region.
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Fig. 2 T2-weighted sagittal
MRI of the left pretibial region showing a
hyperintense well-circumscribed mass extending to
but not traversing the underlying fascia. A
consensual area of hyperintensity of the bone marrow
was seen.
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SGA is a benign, inflammatory lesion
occurring in otherwise healthy preschoolers in the lower
extremity, especially the pretibial area, in hands, scalp
and buttocks. The pathogenesis is unknown, the association
with diabetes mellitus is controversial, and the description
of triggering events like trauma has anecdotal interest. In
this case, the repetitive trauma justified the associated
bone marrow edema. The pediatricians should take care not to
misdiagnose these cases as malignancy, as we did, indicating
unnecessary treatments while spontaneous regression is the
rule.